Any cold damage disease pattern resulting when external evils pass from the exterior to the interior. Evils in the yáng channels are in the interior when in the yáng brightness (yáng míng). For example, yáng brightness (yáng míng) disease with a slow pulse, heavy body, shortness of breath, abdominal fullness and panting, and tidal heat can be treated by attacking the interior with one of the Qì-Coordinating Decoctions (承气汤chéng qì tāng); yáng brightness (yáng míng) with sweating from the head only (absence of generalized sweating), inhibited urination, and thirst with intake of fluid is a sign of stasis heat in the interior that is invariably accompanied by yellowing and is treated with Virgate Wormwood Decoction (茵陈蒿汤yīn chén hāo tāng). If the evils pass from the yáng to the yīn channels, or make a direct strike on the lesser yīn (shào yīn), the resulting patterns are of interior vacuity cold. For example, lesser yīn (shào yīn) disease with sunken rapid fine pulse indicates disease of the interior for which the method of sweating is contraindicated; lesser yīn (shào yīn) disease with clear-grain diarrhea, interior cold and external heat, reverse flow of the extremities, and faint pulse verging on expiration should be treated with Vessel-Freeing Counterflow Cold Decoction (通脉四逆汤tōng mài sì nì tāng). yáng brightness (yáng míng) disease and triple-yīn disease are both interior patterns that are quite different in terms of cold, heat, vacuity, and repletion, so care must be taken in pattern identification and treatment. See cold damage.