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Also passage and transmutation. Any passage from one channel to another or change in the manifestation of disease, i.e., all regular and irregular developments in cold-damage diseases. Shift includes the normal passage of disease through the channels, such as from greater yáng (tài yáng) to yáng brightness (yáng míng) or lesser yáng (shào yáng), and major or irregular changes such as of yáng patterns into yīn patterns or cold-heat complexes.

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